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Gillings School Directory
David Couper, PhD
TODO

David Couper, PhD

Professor
Department of Biostatistics
Deputy Director
Collaborative Studies Coordinating Center
  • Collaborative Studies Coordinating Center
  • 123 W. Franklin Street, Suite 450, CB #8030
  • Chapel Hill, NC 27516
  • USA

Dr. David Couper's faculty appointment is in the Collaborative Studies Coordinating Center (CSCC), a unit in the Department of Biostatistics. 

Dr. Couper has worked at the CSCC since 1998 and has been the coordinating center (CC) Principal Investigator for several clinical trials and observational studies. He is currently PI of the Coordinating Center for the Atherosclerosis Risk in Communities (ARIC) Study, the ARIC Neurocognitive Study (ARIC-NCS) and the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) clinical trial, as well as the PI of the Genomics and Informatics Center for the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).

Representative Courses

Intermediate Statistical Methods (BIOS 662)

Design of Public Health Studies (BIOS 668)

Intermediate Linear Models (BIOS 663)

Research Interests

  • Data Quality
  • Epidemiological Methods
  • Longitudinal Data

Service Activities

Member of the (NIH) National Advisory Dental and Craniofacial Research Council (2018-2021)

Member of the NC TraCS Data and Safety Monitoring Board (DSMB) since 2005

Service on DSMBs for various NIH-funded studies

On the panel of statistical reviewers for Circulation, the Journal of the American Heart Association, and JAMA Network Open, plus reviewing of manuscripts for various other journals

Regular and ad hoc peer reviewer for NHLBI, NIAMS, NIAID, NIAAA, NHGRI, NIDDK (on hold while serving the National Advisory Dental and Craniofacial Research Council)

Peer review for Singapore's National Medical Research Council (on hold while serving the National Advisory Dental and Craniofacial Research Council)

Key Publications

Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). R Barr, E Bleecker, D Couper, M Han, E Hoffman, R Kanner, E Kleerup, L Lavange, F Martinez, S Rennard, P Woodruff (2014). Thorax, 69(5), 492-5.

Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study. Oyenuga A.O. Couper D., Matsushita K., Boerwinkle E., Folsom A.R. (2018). PLoS One, 13(10).

SPIROMICS Research Group. Variability in objective and subjective measures affects baseline values in studies of patients with COPD. Anderson W.H., Ha J.W., Couper D.J., O'Neal W.K., Barr R.G., Bleecker E.R., Carretta E.E., Cooper C.B., Doerschuk C.M., Drummond M.B., Han M.K., Hansel N.N., Kim V., Kleerup E.C., Martinez F.J., Rennard S.I., Tashkin D., Woodruff P.G., Paine R. 3rd, Curtis J.L., Kanner R.E. (2017). PLoS One, 12(9).

Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study. C Ballantyne, E Boerwinkle, D Couper, J Crosby, R Dodge, J Gaubatz, R Hoogeveen, J Jiang, S Kathiresan, W Sun, S Virani (2014). Arteriosclerosis, thrombosis, and vascular biology, 34(5), 1069-77.

Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up. M Albert, A Alonso, K Bandeen-Roche, L Coker, J Coresh, D Couper, R Gottesman, M Griswold, G Heiss, D Knopman, T Mosley, M Patel, A Penman, M Power, A Rawlings, A Schneider, O Selnes, A Sharrett, L Wagenknecht, B Windham, L Wruck (2014). American Journal of Epidemiology, 179(8), 956-966.

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events. L Bouter, I Butcher, J Cauley, D Couper, M Criqui, M Cushman, R D'Agostino, G Debacker, A Folsom, F Fowkes, O Franco, R Hamman, B Hedblad, R Heine, W Hiatt, A Hirsch, A Hofman, M Hunink, J Knottnerus, W Koenig, M Kornitzer, R Langer, A Lee, K Masaki, M McDermott, C Meisinger, J Murabito, G Murray, A Newman, P Norman, M Ogren, J Price, C Stehouwer, H Stoffers, K Sutton-Tyrrell, J Witteman (2014). European journal of preventive cardiology, 21(3), 310-20.

Meta-analysis of loci associated with age at natural menopause in African-American women. C Ambrosone, J Andrews, A Arnold, E Bandera, L Bernstein, A Britton, R Brzyski, A Cappola, C Carlson, G Chen, C Chen, D Couper, L Cupples, E Demerath, S Deming, J Dreyfus, M Evans, N Franceschini, M Garcia, M Goodarzi, C Haiman, T Harris, G Heiss, B Henderson, E John, S Kardia, K Kerr, C Kooperberg, L Le Marchand, G Li, Y Liu, C Liu, K Lohman, X Lu, K Marciante, B McKnight, R Millikan, T Mosley, J Murabito, S Musani, M Nalls, N Nock, A Olshan, M Press, B Psaty, L Raffel, A Rajkovic, J Smith, H Taylor, D Vaiyda, M Wellons, B Windham, N Woods, W Zhao, W Zheng, A Zonderman (2014). Human molecular genetics.

Staff/Administrative Duties

Deputy Director of the Collaborative Studies Coordinating Center

Education

PhD, Biostatistics, University of Washington, 1994

MS, Biostatistics, University of Washington, 1991

MSc, Statistics, University of South Africa, 1982

BS, Mathematical Statistics, University of Cape Town, 1977

BSc, Mathematics, University of Cape Town, 1975

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