Di Wu, PhD

Associate Professor
Department of Biostatistics
Associate Professor
UNC School of Dentistry
385 South Columbia Street
CB #7455
Chapel Hill, NC 27599


Di Wu is a biostatistician working in the bioinformatics field. She has developed novel statistical bioinformatics methods to handle biomedical and genomics data. She also has developed gene set testing methods with high citations, in the empirical Bayesian framework, to take care of small complex design and genewise correlation structure.

Dr. Wu has applied data integration strategy to identify the potential cell of origin for different breast cancer subtypes in silicon (at WEHI). Her recent projects have focused on genomic data based drug repurposing (at Harvard). She is now working on novel mediator analysis-based data integration tools to infer the likely causal relation across multiple levels of genomic, microbiome and metabolites (at UNC).

Her new project has more microbiome and Electrical Medical Records components since the announcement of her joint position in the UNC School of Dentistry the Department of Biostatistics and the Carolina Health Informatics Program in 2015.

Honors and Awards

Early Career Overseas Fellowship
2011, Australian National Health and Medical Research Council

Teaching Interests

Aug. 2016 - present:
Acts as an academic mentor for a public health informatics graduate student through the Carolina Health Informatics Program

2015 - present:
Serves on the dissertation committee for Sarah Kay Youny Lee through the UNC School of Dentistry

Acted as co-adviser for Tanjit S. Taggar through the UNC School of Dentistry

Served on the dissertation committee for Doug Wilson through the Department of Biostatistics

Service Activities

- UNC Biostatistics Computing Committee

Has served as a journal referee for:
- Biometrics
- Nucleic Acids Research
- PLoS Computational Biology
- Bioinformatics
- Statistics in Medicine
- Briefings in Bioinformatics
- BMC Bioinformatics
- Statistics in Biosciences
- PLoS One
- ‘Genomics, Proteomics and Bioinformatics - Elsevier’
- Biomarkers in Cancer
- Evolutionary Bioinformatics
- IEEE/ACM Transactions on Computational Biology and Bioinformatics
- Combinatorial Chemistry & High Throughput Screening
- International Journal of Dentistry
- Cancer Informatics journal supplement (Libertas Academica; was the lead guest editor)


  • PhD, Bioinformatics, University of Melbourne, VIC, Australia, 2011
  • MS, Biostatistics, Case Western Reserve University, 2006
  • BS, Biotechnology, Shanghai Jiao Tong University, Shanghai, China, 1998