David Jay Weber

David Jay Weber, MD

Department of Epidemiology
Charles Addison and Elizabeth Ann Sanders Distinguished Professor of Medicine and Pediatrics
UNC School of Medicine
Associate Chief Medical Officer
UNC Medical Center
Medical Director
Department of Infection Prevention, UNC Medical Center
2153 Bioinformatics Building
CB# 7030
Chapel Hill, NC 27599


Dr. Weber is a professor of medicine, pediatrics and epidemiology, associate chief medical officer of UNC Health Care, and director of regulatory services for the North Carolina Translational and Clinical Sciences Institute (NC TraCS)

NC TraCS is home to the UNC Clinical and Translational Science Award (CTSA) award). Dr. Weber serves as medical director of hospital epidemiology (infection control) and as director of the UNC Health Care Anti - Infective Stewardship (a broad-based program that includes dedicated ID pharmacists, drug information specialists, pediatric and adult infectious disease specialists, and molecular microbiologists).

Dr. Weber is also board certified in internal medicine, infectious disease, critical care medicine and preventative medicine. His research career has focused on healthcare-associated infections, antibiotic stewardship, new and emerging diseases (Pfiesteria, Cryptosporidia, norovirus) and vaccine implementation. Dr. Weber also chairs the North Carolina Department of Health.

David Weber in the Gillings News

Research Activities

Health behavior
Health care delivery
Infectious diseases

Practice Activities


Diplomate, National Board of Medical Examiners, 1977
Diplomate, American Board of Internal Medicine, 1980
American Heart Association, Advanced Cardiac Life Support, 1983
American Heart Association, Advanced Cardiac Life Support, Instructor, 1985
Diplomate, Infectious Disease Boards, American Board of Internal Medicine, 1988
Diplomate, Critical Care Medicine Boards, American Board of Internal Medicine, 1991
Diplomate, Preventive Medicine Boards, American Academy of Preventive Medicine, 1992

Key Publications

Public Health Intelligence: Learning From the Ebola Crisis. Carney TJ, Weber DJ (2015). Am J Public Health, 105(9), 1740-1744.

Changes in cerebellar activation following onabotulinumtoxin A injections for spasticity after chronic stroke: A pilot fMRI study. Chang CL, Weber DJ, Munin MC (2015). Arch Phys Med Rehabil, Epub ahead of print.

Chronic herpes simplex type-1 encephalitis with intractable epilepsy in an immunosuppressed patient. Laohathai C, Weber DJ, Hayat G, Thomas FP (2015). Infection, Epub ahead of print.

Prevalence of Smqnr and plasmid-mediated quinolone resistance determinants in clinical isolates of Stenotrophomonas maltophilia from Japan: novel variants of Smqnr. Kanamori H, Yano H, Tanouchi A, Kakuta R, Endo S, Ichimura S, Ogawa M, Shimojima M, Inomata S, Ozawa D, Aoyagi T, Weber DJ, Kaku M (2015). New Microbes New Infect, 7.

Longitudinal Trends in All Healthcare-Associated Infections through Comprehensive Hospital-wide Surveillance and Infection Control Measures over the Past 12 Years: Substantial Burden of Healthcare-Associated Infections Outside of Intensive Care Units and "Other" Types of Infection. Kanamori H, Weber DJ, DiBiase LM, Sickbert-Bennett EE, Brooks R, Teal L, Williams D, Walters EM, Rutala WA (2015). Infect Control Hosp Epidemiol, 25.


  • MPH, Epidemiology, Harvard University, 1985
  • MD, Medicine, University of California, San Diego, 1977