David G. Kaufman, MD, PhD

Assistant Director
Center for Environmental Health and Susceptibility
620 Brinkhous-Bullitt Building
CB# 7525
Chapel Hill, NC 27599
USA

About

Dr. David G. Kaufman is a professor of pathology and laboratory medicine who has been at the university for more than 40 years. He is involved in the clinical practice of pathology and also teaches residents. He conducts cancer research with particular interests in endometrial cancer and the role of DNA replication and repair in cancer.

Teaching Interests

Dr. Kaufman teaches pathology residents in clinical service and medical students in small group lab sessions; he also lectures in graduate level courses during both academic semesters.

Research Activities

Dr. Kaufman studies the role of interactions between epithelial cells and stromal cells in endometrial tissue with regard to tissue formation, homeostasis, responses to environmental factors and the development of cancer.

Key Publications

SWI/SNF Complexes are Required for Full Activation of the DNA-Damage Response. Smith-Roe, S.L., Nakamura, J., Holley, D., Chastain, P.D., Rosson, G.B., Simpson, D.A., Ridpath, J.R., Kaufman, D.G., Kaufmann, W.K., and Bultman, S.J.  (2014). Oncotarget.

Re-establishment of Gap-Junction Intercellular Communication in Human Endometrial Carcinoma Cells by Prostaglandin E2. Schlemmer, S.R., and Kaufman, D.G. (2012). Experimental and Molecular Pathology, 93.

Genistein Effects on Stromal Cells Determines Epithelial Proliferation in Endometrial Co-Cultures. Sampey, B.P., Lewis, T.D., Barbier, C.S., Makowsk, L, and Kaufman, D.G. (2011). Exp. Mol. Path, 90.

Automated DNA Fiber Tracking and Measurement. Proceedings - International Symposium on Biomedical Imaging. Wang, Y., Chastain, P.D., Yap, P.T., Kaufman, D.G., Guo, L., and Shen, D.  (2011).

Temporal and Functional Analysis of DNA Replicated in Early S Phase. Kaufman, D.G., Cohen, S.M., and Chastain, P.D.  (2011). Adv. Enzyme Regul., 51.

Staff/Administrative Duties

Co-chair of the University's Radiation Safety Committee

Member of the University's Safety and Security Committee

Co-chair of the Medical School's Woods and Jefferson-Pilot Awards Committee

Education

  • PhD, Experimental Pathology, Washington University, 1973
  • Resident, Pathology, Barnes Hospital and Washington Univiversity Hospital, St. Louis, 1970
  • Intern, Pathology, Barnes Hospital and Washington University Hospital, St. Louis, 1969
  • MD, Medicine, Washington University, 1968
  • BA, Physics, Reed College, 1965