Melinda Beck

 

GGG_beck_melinda_01
Associate Department Chair 
Nutrition

Melinda Beck’s Biosketch 
Curriculum Vitae 
REACH NC (Collexis) Research Profile

Office

2303 Michael Hooker Res Bldg 
135 Dauer Drive 
Campus Box 7461 
Chapel Hill 27599 
USA 
T: 919-966-6809 
F: 919-843-0776 
melinda_beck@unc.edu


Education

1987
The Ohio State University
PhD, Medical Microbiology and Immunology

1983
California Polytechnic State University
MS, Biological Sciences

1978
University of California, Berkeley
BA, Zoology


Research activities

Research exploration of the relationship between host nutrition and immune function and response to infectious disease. Research in the laboratory has demonstrated that host deficiencies in antioxidant nutrients lead to viral mutations which results in viruses becoming pathogenic. This was the first description of a specific host nutritional deficiency driving changes in a viral genome permitting an avirulent virus to acquire virulence. Dr. Beck’s laboratory research suggests that host nutritional status is a driving force for the emergence of infectious diseases. Current research is focused on determining the mechanism(s) involved in inducing mutations in viruses which replicate in an oxidatively stressed host as well as understanding the effect of nutritionally-induced oxidative stress on the immune system. In addition, Dr. Beck is studying the effects of obesity on the immune response. Her research indicates that diet-induced obese animals have a much higher mortality rate from influenza infection than lean animals. In addition, obese humans may not respond to influenza virus vaccination as efficiently as lean individuals. Understanding how obesity impacts the immune response to infection is currently under study.