More (single-cell) data, more (statistical) problems
Blue Cross and Blue Shield Auditorium (0001 Michael Hooker Research Center) Michael Hooker Research Center, Chapel Hill, NC, United StatesSingle-cell RNA-Seq(scRNA-seq) is the most widely used high-throughput technology to measure genome-wide gene expression at the single-cell level. However, single-cell data present unique challenges that have required the development of specialized methods and software infrastructure to successfully derive biological insights. Compared to bulk RNA-seq, there is an increased scale of the number of observations (or... Read more »