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More (single-cell) data, more (statistical) problems

February 13, 2020 @ 3:30 pm - 4:30 pm

Flyer for Hicks SeminarSingle-cell RNA-Seq(scRNA-seq) is the most widely used high-throughput technology to measure genome-wide gene expression at the single-cell level. However, single-cell data present unique challenges that have required the development of specialized methods and software infrastructure to successfully derive biological insights. Compared to bulk RNA-seq, there is an increased scale of the number of observations (or cells) that are measured and there is increased sparsity of the data, or fraction of observed zeros. Furthermore, as single-cell technologies mature, the increasing complexity and volume of data require fundamental changes in data access, management, and infrastructure alongside specialized methods to facilitate scalable analyses. Hicks will discuss these challenges and present some solutions that her team has made towards addressing these challenges.

Details

Date:
February 13, 2020
Time:
3:30 pm - 4:30 pm
Event Categories:
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Location

Blue Cross and Blue Shield Auditorium (0001 Michael Hooker Research Center)
Michael Hooker Research Center
Chapel Hill, NC 27516 United States
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