Superfund Research Program Publications

Reflections from the Well is the e-newsletter of the UNC-Superfund Research Program. It is issued quarterly and features significant program accomplishments and highlights the work of several projects and cores in each issue. The newsletter is distributed to elected officials, environmental and community-based organizations, various governmental contacts, other SRPs, etc.

Fall 2021

• Undergraduate interns learn to communicate science while researching environmental exposures
• Where water filters meet computer modeling: Developing molecular simulations to improve in-home filtration systems
• CEC develops digital interactive notebook for science teachers featuring SRP research
• UNC SRP Trainee Spotlight – Eating for two: Changing the mother’s diet as an intervention for prenatal arsenic exposure
• Into the Dataverse: A dataset of Superfund geolocations and their implications for health
• High school students join SRP labs over the summer, a Q&A with Projects 2 & 5

Spring 2021

• Community partners weigh in on needs for interactive mapping tool
• Increasing efficiency of gut microbiome measurements
• Public Health Action Committee advises CEC
• UNC SRP Trainee Spotlight – It’s a Learning Process: Practicing well water sampling methods in the field
• Diversifying STEM researchers

Fall 2020

• Welcome to UNC-SRP
• New mouse model for arsenic exposure research
• UNC-SRP team tackles COVID-19
• Meet our new Public Health Action Committee

Peer-reviewed Publications & Conference Proceeding

2021

Anderson, C., Fry, R.C., Hartwell, H., Kleeberger, C., Sandler, D.P., Nichols, H.B. (2021). Measurement of mitochondrial DNA copy number in dried blood spots: A pilot study. Mitochondrion. DOI: 10.1016/j.mito.2020.11.006

Rebuli, M.E., Glista-Baker, E., Hoffman, J.R., Duffney, P.F., Robinette, C., Speen, A.M., Pawlak, E.A., Dhingra, R., Noah, T.L., Jaspers, I. (2021). Electronic-cigarette use alters nasal mucosal immune response to live-attenuated influenza virus. A clinical trial. American Journal of Respiratory Cell and Molecular Biology. DOI:  10.1165/rcmb.2020-0164OC

Santos Jr, H.P., Bhattacharya, A., Joseph, R.M., Smeester, L., Kuban, K.C.K., Marsit, C.J., O’Shea, T.M., Fry, R.C. (2021). Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm. Molecular Autism. DOI: 10.1186/s13229-020-00402-w

2020

Sigmon, J.S., Blanchard, M.W., Baric, R.S., Bell, T.A., Brennan, J., Brockmann, G.A., Burks, A.W., Calabrese, J.M., Caron, K.M., Cheney, R.E., Ciavatta, D., Conlon, F., Darr, D.B., Faber, J., Franklin, C., Gershon, T.R., Gralinski, L., Gu, B., Gaines, C.H., Hagan, R.S., Heimsath, E.G., Heise, M.T., Hock, P., Ideraabdullah, F., Jennette, J.C., Kafri, T., Kashfeen, A., Kulis, M., Kumar, V., Linnertz, C., Livraghi-Butrico, A., Lloyd, K.C.K., Lutz, C., Lynch, R.M., Magnuson, T., Matsushima, G.K., McMullan, R., Miller, D.R., Mohlke, K.L., Moy, S.S., Murphy, C.E.Y., Najarian, M., O’Brien, L., Palmer, A.A., Philpot, B.D., Randell, S.H., Reinholdt, L., Ren, Y., Rockwood, S., Rogala, A.R., Saraswatula, A., Sassetti, C.M., Schisler, J.C., Schoenrock, S.A., Shaw, G.D., Shorter, J.R., Smith, C.M., St. Pierre, C.L., Tarantino, L.M., Threadgill, D.W., Valdar, W., Vilen, B.J., Wardwell, K., Whitmire, J.K., Williams, L., Zylka, M.J., Ferris, M.T., McMillan, L., Pardo-Manuel de Villena, F. (2020). Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research. Genetics, 216(4), 905-930. DOI: 10.1534/genetics.120.303596

Venkatratnam, A., Douillet, C., Topping, B.C., Shi, Q., Addo, K.A., Ideraabdullah, F.Y., Fry, R.C., Stýblo, M. (2020). Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring. Archives of Toxicology. DOI: 10.1007/s00204-020-02941-w

Yu, W., Hill, S.F., Xenakis, J.G., Pardo-Manuel de Villena, F., Wagnon, J.L., Meisler, M.H. (2020). Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse. Epilepsia, 61(12), 2847-2856. DOI: 10.1111/epi.16741

Rebuli, M.E., Glista-Baker, E., Hoffman, J.R., Duffney, P.F., Robinette, C., Speen, A.M., Pawlak, E.A., Dhingra, R., Noah, T.L., Jaspers, I. (2021). E-cigarette Use Alters Nasal Mucosal Immune Response to Live-Attenuated Influenza Virus (LAIV). American Journal of Respiratory Cell and Molecular Biology, 64(1), 126-137. DOI: 10.1165/rcmb.2020-0164OC

Lebow-Skelley, E., Yelton, S., Janssen, B., Erdei, E., Pearson, M.A. (2020). Identifying Issues and Priorities in Reporting Back Environmental Health Data. International Journal of Environmental Research and Public Health, 17(18), 6742. DOI: 10.3390/ijerph17186742

Gu, B., Shorter, J.R., Williams, L.H., Bell, T.A., Hock, P. Dalton, K.A., Pan, Y., Miller, D.R., Shaw, G.D., Philpot, B.D., Pardo-Manuel de Villena, F. (2020). Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility. Epilepsia, 61(9), 2010-2021. DOI: 10.1111/epi.16617

Douillet, C., Koller, B.H., Stýblo, M. (2020). Metabolism of Inorganic Arsenic in Mice Lacking Genes Encoding GST-P, GST-M, and GST-T. Chemical Research in Toxicology, 33(8), 2043-2046. DOI: 10.1021/acs.chemrestox.0c00273

Gray, K.M., LePrevost, C.E., Cope, W.G. (2020). Anglers’ Views on Using Signs to Communicate Fish Consumption Advisories. Fisheries, 45(10), 307-316. DOI: 10.1002/fsh.10463

Li, Y.Y., Douillet, C., Huang, M., Beck, R., Sumner, S.J., Stýblo, M. (2020). Exposure to inorganic arsenic and its methylated metabolites alters metabolomics profiles in INS-1 832/13 insulinoma cells and isolated pancreatic islets. Archives of Toxicology, 94(6), 1955-1972. DOI: 10.1007/s00204-020-02729-y