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UNC Nutrition Obesity Research Center (NORC)
Nutritional Genomics
and Microbiome Core

About

Researchers evaluate a study.

Researchers evaluate a study.

The Nutritional Genomics and Micriobiome Core is an all-encompassing support system for investigators conducting research on nutrigenetic and microbiome aspects of obesity and obesity-related diseases.

The goal for some obesity research is to identify genetic and environmental factors and interactions that affect an individual’s susceptibility and to identify high-utility targets for prevention and treatment. In the long run, investigators should be able to individualize or personalize diet and health recommendations based on the knowledge gained from prior research conducted on obesity. Thus, there is a great need for studies with strong translational potential. Additionally, the Microbiome sub-core provides consultation (experimental design, grant writing assistance, data interpretation and publication help) on nutrition focused microbiome studies.


Nutritional Genomics and Microbiome Core Services

Grant Writing Assistance and Consultation for Nutrigenetic Research Studies

Proofreading of Manuscripts and Grant Proposals

Project Design Services

Laboratory Analyses

  • One-Carbon Metabolism SNP Chip Microarray:
    This is the MEGAEX microarray (illumina) containing over 2 million human SNPs including many related to one-carbon metabolism.
  • Genomic DNA Extraction:
    DNA is extracted using a column-based method such as Qiagen’s QIAamp DNA Blood Mini Kit (Qiagen).
  • DNA Isolation & Purification
  • PCR Single Nucleotide Polymorphism (SNP) Genotyping for One-Carbon Metabolism:
    Purified genomic DNA from blood or tissues is analyzed by PCR for single nucleotide polymorphisms (SNPs) relating to one carbon metabolism, (e.g.: PEMT rs12325817, CHDH rs12676 and CHDH rs9001).

Brokerage Services

Analytical Services

Training Services


Contact Us

Dr. Saroja Voruganti

Saroja Voruganti, PhD
Assistant Professor, Nutrition
500 Laureate Way, Suite 3150
Kannapolis, NC 28081
(704) 250-5009
saroja@unc.edu

  • Director, Nutritional Genomics and Microbiome Core (Nutrigenetics)
  • See Profile of Saroja Voruganti, PhD here

Dr. Ian Carroll

Ian Carroll, PhD
Assistant Professor, Nutrition
111 Mason Farm Road , 7312C MBRB Building
CB# 7032
Chapel Hill, NC 27599
(919) 843-4893
ian_carroll@med.unc.edu

  • Sub Core Co-Director, Nutritional Genomics and Microbiome Core (Microbiome)
  • See Profile of Ian Carroll, PhD here

Dr. Katie Meyer

Dr. Katie Meyer

Katie Meyer, ScD
Assistant Professor, Nutrition
500 Laureate Way
Kannapolis, NC 28081
(704) 250-5071
ktmeyer@email.unc.edu

  • Sub Core Co-Director, Nutritional Genomics and Microbiome Core (Microbiome)
  • See Profile of Katie Meyer, ScD here