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UNC Nutrition Obesity Research Center (NORC)
Metabolism and Metabolomics Core

About

The Metabolism and Metabolomics Core provides cutting edge nutritional metabolomics services, biochemistry methods, and molecular biology techniques for nutrition research.

The goals of our core are to encourage and facilitate the use of biomarkers for nutritional epidemiological and intervention studies, to provide access to state-of-the-art techniques and equipment to bench scientists, and to provide cost-effective assays for investigators without lab facilities. The core also provides training for students and postdoctoral fellows. With locations at both the Chapel Hill and Nutrition Research Institute (NRI) campuses, we are able to provide a wide array of instrumentation and support to investigators at both locations.

Additionally, metabolomics – the profiling of the many small molecules in blood, urine, or tissues – provides an opportunity for investigators to obtain a snapshot of metabolism. The metabolomics lab, located at NRI, is working to make personalized medicine a reality through metabolomics. Metabolomic analyses provide a more comprehensive view of a patient’s metabolism than the limited measurements of glucose and cholesterol that doctors employ today. Using metabolomics, the lab assesses differences in the metabolic profile of individuals that correlate with states of wellness or disease.

The Atomic Absorption Spectroscopy Lab provides analysis that is used to determine the levels of arsenate, methylated and other organic forms of arsenic in solutions and/or matrices.


Services

The Metabolism and Metabolomics Core offers a variety of services. To learn more about a specific service and/or to submit a service request, visit us on iLab.

  • Aperio ScanScope CS Digital Slide Scanner
  • Aqueous Choline Metabolites
  • Atomic Absorption Spectrometry
  • Choline Metabolites
  • Consultation (Nutritional Biochemistry & Molecular Biology)
  • Cytokines & Adipokines
  • Dimethyl-glycine, Choline and Betaine
  • Drug Abuse Tests
  • FACS Aria III Training
  • Flow Cytometry
  • Fluorescence Activated Cell Sorting
  • Folate Assay (Food or Tissue)
  • Folate Assay (RBC or Plasma)
  • Inflammation (ELISA or RIA)
  • Lipids & Lipid Proteins
  • Methods Development
  • Nutrients
  • Organic Choline Metabolites
  • Other Assays
  • Oxidative Stress
  • PCR, RT-PCR & qRT-PCR
  • Peptide Hormones
  • Phospholipid Fatty Acids
  • Plasma, Serum, & Lymphocytes Separation
  • Protein Estimation by BCA Method
  • RNA Isolation & Purification
  • TMA (TMAO, choline, betaine, creatinine)
  • Use of the Aria III Fluorescence Activated Cell Sorter
  • Zeiss Axio Imager A1 Fluorescence Microscope with Camera (DIY)

Contact Us

Susan Sumner

Dr. Susan Sumner

Susan Sumner, PhD
Professor, Nutrition
500 Laureate Way, Suite 4201
Kannapolis, NC 28081
(704) 250-5066
susan_sumner@unc.edu

  • Director, Metabolism and Metabolomics Core

Mirek Styblo, PhD

Dr. Mirek Styblo

Mirek Styblo, PhD
Professor, Nutrition
Adjunct Associate Professor, Environmental Sciences and
Engineering
2302 Michael Hooker Research Center
CB# 7461
Chapel Hill, NC 27599
(919) 966-5721
styblo@med.unc.edu


Susan McRitchie, MA, MS
Program Manager, Sumner Lab
500 Laureate Way
Kannapolis, NC 28081
(704) 250-5067
susan_mcritchie@unc.edu

  • Core Manager, Untargeted Services (NRI)

Sunil Hwang, PhD
Lab Manager, Zeisel Lab
500 Laureate Way, Suite 2148
Kannapolis, NC 28081
(704) 250-5041
sunil_hwang@unc.edu

  • Core Manager, Targeted Services (NRI)

Interest Form

Metabolism and Metabolomics Core Interest Form

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