TODO
UNC Nutrition Obesity Research Center (NORC)
Metabolomics and Exposome Core

About

The Metabolomics and Exposome Core provides cutting edge nutritional metabolomics services, biochemistry methods and molecular biology techniques for nutrition research.

The goals of our Core are to encourage and facilitate the use of biomarkers for nutritional epidemiological and intervention studies, to provide access to state-of-the-art techniques and equipment to bench scientists, and to provide cost-effective assays for investigators without lab facilities. The Core also provides training for students and postdoctoral fellows. This Core is split between two locations, one at Chapel Hill and one at Kannapolis. This way we are able to provide a wide array of instrumentation and support investigators at either location.

Additionally, metabolomics, the profiling of the many small molecules in blood, urine or tissues, provides an opportunity for investigators to obtain a snapshot of metabolism. The metabolomics lab, located in Kannapolis, NC, is working to make personalized medicine a reality through metabolomics. Metabolomic analyses provide a more comprehensive view of a patient’s metabolism than the limited measurements of glucose and cholesterol that doctors employ today. Using metabolomics, the lab assesses differences in the metabolic profile of individuals that correlate with states of wellness or disease.


Services

Please visit our website to order and learn more about our services.

  • Aperio ScanScope CS Digital Slide Scanner
  • Aqueous Choline Metabolites
  • Atomic Absorption Spectrometry
  • Choline Metabolites
  • Consultation (Nutritional Biochemistry & Molecular Biology)
  • Cytokines & Adipokines
  • Dimethyl-glycine, Choline and Betaine
  • Drug Abuse Tests
  • FACS Aria III Training
  • Flow Cytometry
  • Fluorescence Activated Cell Sorting
  • Folate Assay (Food or Tissue)
  • Folate Assay (RBC or Plasma)
  • Inflammation (ELISA or RIA)
  • Lipids & Lipid Proteins
  • Methods Development
  • Nutrients
  • Organic Choline Metabolites
  • Other Assays
  • Oxidative Stress
  • PCR, RT-PCR & qRT-PCR
  • Peptide Hormones
  • Phospholipid Fatty Acids
  • Plasma, Serum, & Lymphocytes Separation
  • Protein Estimation by BCA Method
  • RNA Isolation & Purification
  • TMA (TMAO, choline, betaine, creatinine)
  • Use of the Aria III Fluorescence Activated Cell Sorter
  • Zeiss Axio Imager A1 Fluorescence Microscope with Camera (DIY)

Contact Us

Susan Sumner

Susan Sumner

Susan Sumner, PhD
Professor, Nutrition
500 Laureate Way, Suite 4201
Kannapolis, NC 28081
(704) 250-5066
susan_sumner@unc.edu

  • Director, Metabolomics and Exposome Core

Dr. Melinda Beck

Dr. Melinda Beck

Melinda Beck, PhD
Associate Chair for Academics
and Professor, Nutrition
2303 Michael Hooker Research Center
CB# 7461
Chapel Hill, NC 27599
(919) 966-6809
melinda_beck@unc.edu

  • Co-Director, Targeted Metabolic Profiling Sub-Core (Chapel Hill)

Dr. Steven Zeisel

Dr. Steven Zeisel

Steven Zeisel, MD, PhD
Kenan Distinguished Professor, Nutrition and Pediatrics
2115-A Michael Hooker Research Center
CB# 7461
Chapel Hill, NC 27599
(919) 843-4731
steven_zeisel@unc.edu

  • Co-Director, Targeted Metabolic Profiling Sub-Core (Kannapolis)

Mirek Styblo, PhD

Mirek Styblo, PhD

Mirek Styblo, PhD
Professor, Nutrition
Adjunct Associate Professor, Environmental Sciences and
Engineering
2302 Michael Hooker Research Center
CB# 7461
Chapel Hill, NC 27599
(919) 966-5721
styblo@med.unc.edu

  • Director, Atomic Absorption Spectrometry Lab

Susan McRitchie
Program Manager, Sumner Lab
500 Laureate Way
Kannapolis, NC 28081
(704) 250-5067
susan_mcritchie@unc.edu

  • Core Manager, Metabolomics and Exposome Core

Sunil Hwang
Lab Manager, Zeisel Lab
500 Laureate Way, Suite 2148
Kannapolis, NC 28081
(704) 250-5041
sunil_hwang@unc.edu

  • Core Manager, Targeted Metabolic Profiling Sub-Core (Kannapolis)

Qing Shi, MS
Research Technician
2215 Michael Hooker Research
Center
CB# 7461
Chapel Hill, NC 27599
(919) 966-7162
qing_shi@unc.edu

  • Core Manager, Targeted Metabolic Profiling Sub-Core (Chapel Hill)
  • Contact for all questions regarding the Core and/or services in Chapel Hill

Interest Form

Metabolomics and Exposome Core Interest Form

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