 Dr. Lawrence L. Kupper, Alumni Distinguished Professor of Biostatistics, has recently co-authored a book with Dr. Stephen M. Rappaport of the University of California, Berkeley. Published in March of 2008, this book is entitled Quantitative Exposure Assessment, and it describes about two decades of published collaborative research work between Drs. Kupper and Rappaport describing state-of-the-art quantitative methods for examining levels of chemical exposures and their effects in human populations. The book has been published by Lulu Press, an online publishing company. Selected topics include historical developments of sampling strategies and occupational exposure limits, methods for characterizing lognormally distributed exposure levels within and between persons and across groups, the integration of exposure assessment with control options, assessment of the effects of exposure measurement error, the development of toxicokinetic methods for relating levels of chemical exposures to corresponding dose levels, and a comparison between air and biomarker measurements as surrogates for true exposure levels. To illustrate the application of the research methods discussed in the book, extensive use is made of numerous data sets obtained from populations exposed to air contaminants. |
