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Center for Environmental Health and Susceptibility
UNC Center for Environmental Health and Susceptibility

NEW – 2019-2020 Pilot Project Grants Available!

2019-2020 CEHS Pilot Project Application Guidelines
Letter of Intent Due December 21, 2018 – Application due January 22, 2019

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Facilitating Environmental Exposure Research

Creating research collaborations and encouraging new environmental exposure researchers can advance environmental health sciences. The UNC Center for Environmental Health and Susceptibility facilitates these collaborations by funding university infrastructure to support scientific equipment, facilities, and other resources that can be shared among environmental health researchers. By pursuing shared research questions, CEHS can identify emerging issues that advance understanding about how pollutants and other environmental factors affect human biology and may lead to disease.  The Center is funded through a P-30 grant from the National Institutes of Environmental Health Sciences.

Message from the Director

Dr. Melissa Troester
Dr. Melissa Troester, Director
"The Center for Environmental Health and Susceptibility (CEHS) is part of one of the most critical public health efforts in history, investigating environmental exposures and their effects on human health." Read more.

Research Highlight

Reproductive Toxicology, March 2018

Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme.

Folami Ideraabdullah, PhD, Assistant Professor
Genetics and Nutritional Research Institute, UNC-CH

In utero exposure to vinclozolin (VIN), an antiandrogenic fungicide, is linked to multigenerational phenotypic and epigenetic effects. Mechanisms remain unclear. We assessed the role of antiandrogenic activity and DNA sequence context by comparing effects of VIN vs. M2 (metabolite with greater antiandrogenic activity) and wild-type C57BL/6 (B6) mice vs. mice carrying mutations at the previously reported VIN-responsive H19/Igf2 locus. Findings demonstrate that maternal effects and crossing scheme play a major role in multigenerational response to in utero exposures.

Link to PubMed article
2018 Mar 10;78:9-19. doi: 10.1016/j.reprotox.2018.03.005. [Epub ahead of print]

 

Outreach Highlight

Climate LEAP alumna receives 2017 President’s Environmental Youth Award

Emily Liu, an alumna of the Institute for the Environment’s 2017 Climate Leadership and Energy Awareness Program (Climate LEAP) and a senior at East Chapel Hill High School (ECHHS), recently received the President’s Environmental Youth Award (PEYA) for her project “Climate Leadership and Outreach: Connecting Air Quality and Renewable Energy.” The 2017 PEYA award recognized 16 outstanding environmental projects by K-12 students
from all 50 states and U.S. territories that promoted awareness of natural resources and encouraged positive community involvement. The EPA recognized national winners of the2017 PEYA at a ceremony in Washington, D.C. on Sept. 21.

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