Paul Stewart, PhD

Research Professor Department of Biostatistics

T:(919) 966-7276

Paul_Stewart@unc.edu

3105G McGavran-Greenberg Hall

CB #7420

Chapel Hill, NC 27599

USA

Dr. Paul Stewart is a research professor in the Department of Biostatistics. His expertise and interests in the development and application of statistical methods for design and analysis of biomedical studies are well-suited for biomedical research, collaboration and consultation.

He has more than 30 years of experience in research design, statistical computation, interpretive analysis, data management and collaboration with biomedical investigators. He has more than 10 years of experience teaching graduate courses in the advanced theory of statistical models in the UNC Department of Biostatistics. He has more than 20 years of experience directing biostatistics cores in programs such as the UNC General Clinical Research Center, UNC Center for AIDS Research, NIH Multicenter DELTA Program and NHLBI-UNC Pediatric Pulmonary SCORE.

Honors and Awards

Scientific Achievement Award for Publication
1997, US-EPA

Associate Editor
Pediatric Pulmonology

NIH Training Grant
The Honor Society for Public Health Professionals

Faculty Award
Delta Omega

Representative Courses

Principles of Statistical Consulting (BIOS 841)

Teaching Interests

Dr. Stewart's experience in teaching has been in a variety of settings within and apart from the School of Public Health. Most of his experience has occurred in the process of training and supervising a large number of students of biostatistics who have worked with Dr. Stewart on collaborative bio-medical research projects as graduate research assistants (GRAs). This activity has involved thousands of hours of direct, practical training and instruction in statistical methods, research database management, statistical computing, consulting skills, and scientific writing.

In addition, Dr. Stewart has directed the thesis research of seven students of biostatistics (BIOS 393 and BIOS 394) and has served as an active member of more that 30 other thesis committees. Dr. Stewart has also supervised the required practical consulting experiences (BIOS 242) of 15 students.

Dr. Stewart has also provided approximately 355 credit hours of instruction in the classroom setting (credit hours per student × number of students) and has provided tutorials and seminars to groups and clients in the Schools of Medicine, Dentistry, Pharmacy and Public Health and to other groups apart from the UNC system.

Research Activities

Incomplete or Censored Data

Adaptive Study Designs

Longitudinal Data Analysis

Linear and Nonlinear Models

Environmental and Biomedical Research

Clinical Trials

Service Activities

Referee of submitted articles for the following journals:
JASA
Biometrics
Technometrics
American Statistician
Pediatric Pulmonology
Statistics & Computing
Environmental Statistics
Journal of Dental Research
American Journal of Respiratory and Critical Care Medicine

Member of the following professional societies:
American Statistical Association (ASA)
Publication Officer of the ASA Section on Statistical Consulting (2007 and 2008) International Biometric Society
Association of GCRC and CTSA Statisticians (gcrc-ags@med.unc.edu)
Founder (2002) and member of the Association of CFAR Statisticians (cfar_stat@med.unc.edu)

Staff/Administrative Duties

2006-present Member Biostatistics Information Technology
1992-2006 Chairman Biostatistics Information Technology
2003 Chairman Committee on Continuation of Business / Emergency Response
1991 Chairman Biostatistics Seminar Committee
1990-1991 Advisor Biostatistics Advisory Committee on Information Technology
1989-1997 Member Biostatistics Seminar Committee
1985-1991 Member Examinations Committee
1982-1992 Member Statistical Computing and Data Management Committee
1985-1986 Member Linear Models Courses Committee (ad hoc)
1994-1995 Member SPH Dean's Computer & Data Processing Advisory Committee
1996 Member SPH Dean's Committee for Review of Information Technology

Key Publications

An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR-rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. KLR Brouwer, R Hardwick, N Pfeifer, P Stewart, K Yang, W Yue (2014). Molecular Pharmaceutics, 11(3), 766-775.

An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Kim Brouwer, Rhiannon Hardwick, Nathan Pfeifer, Paul Stewart, Kyunghee Yang, Wei Yue (2014). Molecular Pharmaceutics, 11(3), 766-775.

Cantharidin for the treatment of molluscum contagiosum: A prospective, double-blinded, placebo-controlled trial. Jacquelyn Dosal, Ja-An Lin, Dean Morrell, Paul Stewart, Christianna Williams (2014). Pediatric Dermatology, 31(4), 440-449.

Correction to "The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans" (Drug Metabolism & Disposition (2013) 41 (575-581) DOI: 10.1124/dmd.112. 048108). M.L. Chen, R.L. Hawke, J.H. Hull, K. IIic, A.D. Kashuba, C.M. Lindley, E.G. Schuetz, P.W. Stewart, R.K. Thirumaran (2014). Drug Metabolism and Disposition, 42(7), 1137-.

Monthly haemostatic factor variability in women and men. Patricia Elmer, Abby Ershow, Mark Fung, Henry Ginsberg, Alison Hill, Stephen Holleran, Penny Kris-Etherton, Michael Lefevre, Thomas Pearson, Roberta Reed, Paul Stewart, Russell Tracy (2014). European Journal of Clinical Investigation, 44(3), 309-318.

Education

PhD, Biostatistics, University of North Carolina at Chapel Hill, 1981

MS, Statistics, University of North Carolina at Chapel Hill, 1977

BS, Mathematics, Furman University, 1975