Patricia Basta, PhD

About

Dr. Patricia V. Basta is a clinical assistant professor of epidemiology at the University of North Carolina at Chapel Hill's Gillings School of Global Public Health.

Biorepository science research, biomarker discovery and genetic epidemiology are the three current themes of Dr. Basta's research. In the past she has also focused on the effects of drugs of abuse and pesticides on neonatal development.

Dr. Basta is available to lend advice and consultation on all aspects of biospecimen collection, processing, storage and biomarker analysis for large and small epidemiology studies.

Teaching Interests

Dr. Basta has provided guest lectures in epidemiology courses dealing with biomarkers.

Research Activities

Research Interests:

1. Biorepository science
2. Genetic epidemiology
3. Neonatal development

Research Activities:

1. Biospecimen processing-methods development
2. Biomarker discovery

Key Publications

Optimized method for DNA extraction from saliva and other non-blood sources. Basta PV, DeJong, H, Lopez A B, Molecular Medicine Tri-Conference, San Francisco, CA, February 9-14, 2014 ..

Long-term storage of Puregene® blood cell lysates and DNA extraction processing in a developing nation setting. Basta P V (speaker & poster), Dominguez R, Heidt P, Castellanos L, Morgan D R. CHI Biorepository Conference, December 2012..

Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). N Alexis, P Basta, J Brown, E Carretta, D Couper, S Crudgington, J Curtis, C Doerschuk, C Freeman, A Hastie, R Kaner, W O'Neal, R Paine Iii, S Rennard, D Shimbo, J Sonstein, V Stolberg, P Woodruff, M Zeidler (2015). Journal of translational medicine, 13(1), 19.

Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. W Anderson, R Barr, P Basta, E Bleecker, E Carretta, S Christenson, D Couper, J Curtis, S Davis, C Doerschuk, M Han, N Hansel, R Kanner, E Kleerup, F Martinez, B Miller, W O'Neal, S Peters, S Rennard, M Scholand, R Tal-Singer, P Woodruff (2014). Journal of translational medicine, 12.

Preliminary examination of polymorphisms of GSTM1, GSTT1, and GSTZ1 in relation to semen quality. P Basta, R Chan, D DeMarini, N Hanley, A Herring, T Luben, A Olshan, S Perreault (2010). Mutation research, 688(1), 41-6.

Genetic variation in Transaldolase 1 and risk of squamous cell carcinoma of the head and neck. P Basta, J Bensen, A Olshan, C Perou, P Sullivan, C Tse (2008). Cancer detection and prevention, 32(3), 200-8.

Education