Full Menu Close Menu


Lisa Smeester, MS

Program Manager, Institute for Environmental Health Solutions Department of Environment Sciences and Engineering

T:(919) 843-8471


346C Rosenau Hall

CB# 7431

Chapel Hill, NC 27599


In addition to serving as Program Manager for the Institute for Environmental Health Solutions, Ms. Smeester actively collaborates with the UNC Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, as well as with the Elgan3-Environmental influences on Child Health Outcomes (ECHO) study. Her research interests include using systems biology and toxicogenomic approaches to investigate epigenetic mechanisms of metal-induced disease, with a focus on prenatal and early life exposures as they relate to the Developmental Origins of Health and Disease (DOHaD).
She has authored numerous peer-reviewed publications and book chapters and is a member of the American Association for the Advancement of Science, the Association for Women in Science, the Genetics and Environmental Mutagenesis Society of NC for which she serves as Treasurer, the Society of Toxicology, and the United States Society for Developmental Origins of Health and Disease.

Lisa Smeester works with Dr. Rebecca Fry and others as part of the Institute for Environmental Health Solutions.

Honors and Awards

Employee Excellence Award
2017, Department of Environmental Sciences & Engineering, UNC Gillings School of Global Public Health

Star Heel Award
2010, Department of Environmental Sciences & Engineering, UNC Gillings School of Global Public Health

Altered DNA Methylation Patterns in Individuals with Arsenicosis, Best Poster Presentation
2010, Genetics and Environmental Mutagenesis Society of North Carolina, Durham,

Key Publications

Long-term Health Effects and Underlying Biological Mechanisms of Developmental Exposure to Arsenic. Smeester L, Fry RC.  (2018). Curr Environ Health Rep, 5(1), 134-144.

Toxic metals in amniotic fluid and altered gene expression in cell-free fetal RNA. Smeester L, Martin EM, Cable P, Bodnar W, Boggess K, Vora NL, Fry RC (2017). Prenat Diagn, 13(.), 1364-1366.

Chronic early childhood exposure to arsenic is associated with a TNF-mediated proteomic signaling response. Smeester L, Bommarito PA, Martin EM, Recio-Vega R, Gonzalez-Cortes T, Olivas-Calderon E, Lantz RC, Fry RC (2017). Environ Toxicol Pharmacol, 52(.), 183-187.

Imprinted genes and the environment: links to the toxic metals arsenic, cadmium, and lead. Smeester L, Yosim AE, Nye MD, Hoyo C, Murphy SK, Fry RC (2014). Genes, 5(2), 477-496.

Epigenetic changes in individuals with arsenicosis. Chemical research in toxicology. *Smeester L, Rager JE, Bailey KA, Guan X, Smith N, Garcia-Vargas G, Del Razo LM, Drobna Z, Kelkar H, Styblo M, Fry RC (2011). Chemical research in toxicology, 24(2), 165-167.


MS, Environmental Sciences and Engineering, UNC Gillings Schools of Global Public Health, 2016

BS, Joint Concentration in Psychobiology, Simmons College, 1995