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Janice S. Lee, PhD

Adjunct Associate Professor Department of Environmental Sciences & Engineering

T:(919) 541-9458


Janice S. Lee, Ph.D., is a Health Scientist at the U.S. EPA’s National Center for Environmental Assessment (NCEA), Integrated Risk Information System (IRIS) Program. Dr. Lee was a toxicologist at the Division of Public Health in Madison, Wisconsin from 2002-2005. She was the technical consultant for environmental exposure assessment and health risk assessment, as well as being the lead toxicologist for developing the public health response to chemical hazards and threats. Prior to joining NCEA in 2008, Dr. Lee was a postdoctoral fellow in the Toxicogenomics Core in the National Health and Environmental Effects Research Laboratory (NHEERL) at EPA where she received training in aging/lifestages and transcriptomics. Dr. Lee received her Ph.D. in Environmental Health Sciences from the University of Michigan in 2002 where her doctoral work focused on arsenic chemistry and health effects. She is interested in susceptibility and the application of novel methods to improve human health risk assessment. She is currently leading the IRIS Toxicological Review of tert-butanol, and is co-chemical manager of the inorganic arsenic toxicological review.

Honors and Awards

Honorable Mention Scientific and Technological Achievement Awards
2011, 2013, US Environmental Protection Agency (US EPA)

Bronze Medal
2012, US Environmental Protection Agency (US EPA)

Research Activities

•    Human health risk assessment
•    Susceptibility
•    Mode of action
•    Systematic review

Key Publications

Relationships between arsenic concentrations in drinking water and lung and bladder cancer incidence in U.S. counties. Mendez W, Eftim S, Cohen J, Warren I, Cowden J, Lee JS, Sams R.  (2016). Journal of Exposure Science and Environmental Epidemiology - advance online publication, doi: 10.1038/jes.2016.58(-).

Systematic review of differential inorganic arsenic exposure in minority, low-income, and indigenous populations in the United States. Joca L, Sacks J, Moore D, Lee JS, Sams R, Cowden J. (2016). Environment International, 92-93(-), 707-715.

Transcriptional ontogeny of the developing liver. Lee JS, Ward WO, Knapp G, Ren H, Vallanat B, Abbott B, Karp SJ, and Corton JC (2012). BMC Genomics, 13(33).

Meta-analysis of microarray data to identify genes altered during normal aging and longevity. Lee JS, Ward WO, Ren H, Vallanat B, Darlington GJ, Han ES, Laguna JC, DeFord JH, Papaconstantinou J, Selman C, Corton JC (2012). Mechanisms of Ageing and Development, 133(7), 467-78.

Hepatic xenobiotic metabolizing enzyme and transporter gene expression through the life stages of the mouse. Lee JS, Ward WO, Liu J, Ren H, Vallanat B, Delker D, Corton JC (2011). PLoS ONE, 6(9), e24381.


PhD, Environmental Health Sciences, University of Michigan at Ann Arbor, 2002

MHS, Environmental Health Sciences, Johns Hopkins University, 1998

BS, Biochemistry, State University of New York at Binghamton, 1997