Gillings School Directory
Anastasia Ivanova, PhD
Anastasia Ivanova, PhD
Professor
Department of Biostatistics
Dr. Anastasia Ivanova is a professor in the Department of Biostatistics. Dr. Ivanova has more than 20 years of experience in designing and conducting clinical trials. She is currently a Principal Investigator (PI) of the Data, Modeling, and Coordinating Center for Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network. The project was awarded by NHLBI to conduct an adaptive precision medicine trial to identify novel treatments for severe asthma. She is also a co-PI of Back Pain Consortium (BACPAC) Research Program Data Integration, Algorithm Development and Operations Management Center (DAC).
Honors and Awards
Stanley S. Schor scholarship to work on adaptive designs2006 – 2007, Merck Research Laboratories
Fellow2020, American Statistical Association
Representative Courses
Probability and Statistical Inference I (BIOS 660) (BIOS 672)
Design and Analysis of Clinical Trials (BIOS 752)
Research Interests
- Adaptive Designs
- Dose-finding Methods
- Enrichment Designs
Service Activities
Associate Editor, Statistics in Medicine, 2006 – Present
Associate Editor, Biometrics, 2011 – 2013
NC ASA chapter Vice President, 2015
NC ASA chapter President, 2016
Key Publications
A two-way enriched clinical trial design: combining advantages of placebo lead-in and randomized withdrawal. Ivanova, A., Tamura, R.N. (2015). Statistical Methods in Medical Research.
Dose-finding for binary ordinal and continuous outcomes with monotone objective function: a unified approach. Ivanova, A., Kim, S. (2009). Biometrics, 65.
Continuous toxicity monitoring in phase I trials in oncology. Ivanova, A., Qaqish, B.F., Schell, M.J. (2005). Biometrics, 61.
Higher order response adaptive urn designs for clinical trials with highly successful treatments. Ivanova, A., Hoberman, S. (2015). JRSS C.
Optimality, sample size and power calculations for the sequential parallel comparison design. Ivanova, A., Qaqish, B.F., Schoenfeld, D. (2011). Statistics in Medicine, 30.
Education
PhD, Statistics, University of Maryland, 1998
PhD, Mathematics, St. Petersburg State University, 1992
MS, Mathematics, St. Petersburg State University, 1988
