Anastasia Ivanova, PhD

Associate Professor Department of Biostatistics

T:(919) 843-8086

3103-C McGavran-Greenberg Hall

CB #7420

Chapel Hill, NC 27599


Dr. Anastasia Ivanova has been on faculty at UNC-Chapel Hill since 1999. Her main research area is design and analysis of clinical trials including adaptive and Bayesian trials. These and other topics are covered in the clinical trials course she has been teaching since 2007.

Honors and Awards

Stanley S. Schor scholarship to work on adaptive designs
2006 – 2007, Merck Research Laboratories

Representative Courses

Probability and Statistical Inference I (BIOS 660)

Design and Analysis of Clinical Trials (BIOS 752)

Research Activities

Adaptive designs, Enrichment designs, Randomization, Dose-finding methods, Bayesian methods

Service Activities

Editorial Service
     Associate Editor, Statistics in Medicine, 2006 – present

Key Publications

A two-way enriched clinical trial design: combining advantages of placebo lead-in and randomized withdrawal. Ivanova, A., Tamura, R.N. (2015). Statistical Methods in Medical Research.

Higher order response adaptive urn designs for clinical trials with highly successful treatments. Ivanova, A., Hoberman, S. (2015). JRSS C.

Optimality, sample size and power calculations for the sequential parallel comparison design. Ivanova, A., Qaqish, B.F., Schoenfeld, D. (2011). Statistics in Medicine, 30.

Dose-finding for binary ordinal and continuous outcomes with monotone objective function: a unified approach. Ivanova, A., Kim, S.  (2009). Biometrics, 65.

Continuous toxicity monitoring in phase I trials in oncology. Ivanova, A., Qaqish, B.F., Schell, M.J. (2005). Biometrics, 61.


PhD, Statistics, University of Maryland, 1998

PhD, Mathematics, St. Petersburg State University, 1992

MS, Mathematics, St. Petersburg State University, 1988