Gillings School Directory

Anastasia Ivanova, PhD

Dr. Anastasia Ivanova

Anastasia Ivanova, PhD

Department of Biostatistics
  • 3103-C McGavran-Greenberg Hall
  • CB #7420
  • Chapel Hill, NC 27599
  • USA

Dr. Anastasia Ivanova is a professor in the Department of Biostatistics.

Dr. Ivanova has more than 20 years of experience in designing and conducting clinical trials. She is currently a co-PI of the Data, Modeling, and Coordinating Center for Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network. The project was awarded by NHLBI to conduct an adaptive precision medicine trial to identify novel treatments for severe asthma.

Honors and Awards

Stanley S. Schor scholarship to work on adaptive designs

2006 – 2007, Merck Research Laboratories

Representative Courses

Probability and Statistical Inference I (BIOS 660) (BIOS 672)

Design and Analysis of Clinical Trials (BIOS 752)

Research Interests

  • Adaptive Designs
  • Bayesian Methods
  • Dose-finding Methods
  • Enrichment Designs

Service Activities

Associate Editor, Statistics in Medicine, 2006 – Present

Associate Editor, Biometrics, 2011 – 2013

NC ASA chapter Vice President, 2015

NC ASA chapter President, 2016

Key Publications

A two-way enriched clinical trial design: combining advantages of placebo lead-in and randomized withdrawal. Ivanova, A., Tamura, R.N. (2015). Statistical Methods in Medical Research.

Dose-finding for binary ordinal and continuous outcomes with monotone objective function: a unified approach. Ivanova, A., Kim, S.  (2009). Biometrics, 65.

Continuous toxicity monitoring in phase I trials in oncology. Ivanova, A., Qaqish, B.F., Schell, M.J. (2005). Biometrics, 61.

Higher order response adaptive urn designs for clinical trials with highly successful treatments. Ivanova, A., Hoberman, S. (2015). JRSS C.

Optimality, sample size and power calculations for the sequential parallel comparison design. Ivanova, A., Qaqish, B.F., Schoenfeld, D. (2011). Statistics in Medicine, 30.


PhD, Statistics, University of Maryland, 1998

PhD, Mathematics, St. Petersburg State University, 1992

MS, Mathematics, St. Petersburg State University, 1988

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