Zuzana Drobna, PhD
|Research Assistant Professor
Slovak Academy of Sciences, Bratislava, Slovakia
Dr. Drobna’s research at UNC-CH has been focused on the investigation of metabolism, mode of action, and biomarkers of biological effects of arsenic in primary human hepatocytes and genetically modified cell cultures. In collaboration with Dr. Miroslav Styblo she is looking for the linkage between genetic polymorphism and susceptibility to toxic and cancer promoting effects in individuals exposed to arsenic. Dr. Drobna is a recipient of the Marilyn Gentry Fellowship Program in Nutrition and Cancer supported by the American Institute for Cancer Research/World Cancer Research Fund. She is carrying out research on the effects of specific nutrients and food components on the membrane transport and metabolism of arsenic in human cells. Her research interests include the molecular mechanism of arsenic trioxide in the treatment of acute promyelocytic leukemia and multidrug resistance associated with overexpression of membrane transporters, P-glycoprotein and MRP1, in cancer cells. Dr. Drobna is a member of the Society of Toxicology and the Genetics and Environmental Mutagenesis Society.