Stephanie Engel, PhD

Associate Professor
EpidemiologyCurriculum Vitae
McGavran-Greenberg Hall, 2104C
Campus Box Campus Box 7435
Chapel Hill 27599-7435

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2003 University of North Carolina, Chapel Hill PhD, Epidemiology
2000 University of North Carolina, Chapel Hill MSPH, Epidemiology
1997 University of California at San Diego BS, Animal Physiology and Neuroscience
1997 University of California at San Diego BA, Psychology
Research interests

  • Child development
  • Environment (general)
  • Maternal health
  • Reproductive health
Research activities

Dr. Engel’s research considers the impact of environmental exposures and innate susceptibility factors on adverse pregnancy outcomes and neurodevelopmental impairment in children. She has multiple studies of maternal and child genetic variability in relation to prematurity, growth restriction, preeclampsia and gestational hypertension. The major goal of these projects is to examine the contribution of genetic variation in gene pathways thought to be activated by xenobiotic exposures on risk of adverse pregnancy outcomes in both a North Carolina and Norwegian population. Dr. Engel is also actively engaged in children’s environmental health research. In particular, she has conducted studies of prenatal exposure to endocrine disrupting chemicals and pesticides in relation to neonatal, infant and child neurodevelopment. She is particularly engaged in efforts to better characterize the mechanistic relations between endocrine disrupting exposures and neurodevelopment, and in methodological studies to develop improved exposure assessment techniques during pregnancy.

Key publications
Engel SM, Miodovnik A, Canfield RL, Zhu C, Silva M, Calafat AI, Wolff MS (2010)
Prenatal Phthalate Exposure is Associated with Childhood Behavior and Executive Functioning.
Environmental Health Perspectives: vol.118, p.565-71.

Engel SM, Janevic T, Stein C, Savitz D (2009)
Maternal smoking, preeclampsia, and infant health outcomes in New York City, 1995-2003.
American Journal of Epidemiology: vol.169, p.33-40.

Engel SM; Berkowitz GS; Barr DB; Teitelbaum S; Siskind J; Meisel S; Wetmur JG; Wolff MS (2007)
Prenatal Exposure to Organophosphates and Organochlorines and Performance on the Brazelton Neonatal Behavioral Assessment Scale.
American Journal of Epidemiology: vol.165, p.1397-1404.

Engel SM, Olshan AF, Siega-Riz AM, Savitz DA, Chanock SJ (2006)
Polymorphisms in Folate Metabolizing Genes and Risk for Spontaneous Preterm and Small-for-Gestational Age Birth.
Am J Obstet Gynecol: vol.195, p.1231.e1-11.

Engel SA, Erichsen HC, Savitz DA, Thorp J, Chanock SJ, Olshan AF (2005)
Risk of Spontaneous Preterm Birth is Associated with Common Pro-Inflammatory Cytokine Polymorphisms.
Epidemiology: vol.16, p.469-77.