Ivan Rusyn



Environmental Sciences and Engineering

Ivan Rusyn’s Biosketch 
Ivan Rusyn’s website 
Curriculum Vitae 
Rusyn Laboratory Home Page 
REACH NC (Collexis) Research Profile



0031 Hooker Research Lab 
135 Dauer Drive 
Campus Box 7431 
Chapel Hill 27599 
T: 919-843-2596 
F: 919-843-2596 


1994  Ukrainian State Medical University, Kiev, Ukraine  MD, Medicine

2000  University of North Carolina at Chapel Hill  PhD, Toxicology


ENVR442  Biochemical and Molecular Toxicology

ENVR722  Toxicology Seminar

 Research Interests


Environment (general) 

 Research Activities

The research focus of my laboratory is to apply genomics approaches to understand the molecular mechanisms of chemical-induced carcinogenesis. Specifically, we are interested in nuclear receptor-mediated pathways, DNA damage and repair, and the role of diet in cancer. Through a combination of in vivo animal studies and experiments that utilize cellular and molecular models we aim to better understand why certain chemicals cause cancer in rodents and whether humans are at risk from similar exposures.

Key Publications

Lonsdale J. et a; (2013) 
The Genotype-Tissue Expression (GTEx) project
Nature Genetics: vol.45, p.580-585.

Soldatow V. Y. et al. (2013) 
In vitro models for liver toxicity testing
Toxicology Research: vol.2, p.23-39.

Rusyn I. and Bataller, R. (2013) 
Alcoholand toxicity
Journal of Hepatology

Uehara T., et al. (2013) 
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis
Toxicological Sciences: vol.132, p.53-63.

Rusyn I. and Pogribny I.P. (2013) 
Environmental toxicants, epigenetics, and cancer.
Advances in Experimnetal Medicine and Biology: vol.754, p.215-232.