Environmental Sciences and Engineering
0031 Hooker Research Lab
1994 Ukrainian State Medical University, Kiev, Ukraine MD, Medicine
2000 University of North Carolina at Chapel Hill PhD, Toxicology
ENVR442 Biochemical and Molecular Toxicology
ENVR722 Toxicology Seminar
The research focus of my laboratory is to apply genomics approaches to understand the molecular mechanisms of chemical-induced carcinogenesis. Specifically, we are interested in nuclear receptor-mediated pathways, DNA damage and repair, and the role of diet in cancer. Through a combination of in vivo animal studies and experiments that utilize cellular and molecular models we aim to better understand why certain chemicals cause cancer in rodents and whether humans are at risk from similar exposures.
Lonsdale J. et a; (2013)
The Genotype-Tissue Expression (GTEx) project.
Nature Genetics: vol.45, p.580-585.
Soldatow V. Y. et al. (2013)
In vitro models for liver toxicity testing.
Toxicology Research: vol.2, p.23-39.
Rusyn I. and Bataller, R. (2013)
Journal of Hepatology
Uehara T., et al. (2013)
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Toxicological Sciences: vol.132, p.53-63.
Rusyn I. and Pogribny I.P. (2013)
Environmental toxicants, epigenetics, and cancer..
Advances in Experimnetal Medicine and Biology: vol.754, p.215-232.