Natalia I. Krupenko, PhD

Assistant Professor Department of Nutrition

T:(704) 250-5054

F:(704) 250-5001

natalia_krupenko@unc.edu

500 Laureate Way

Nutrition Research Institute

University of North Carolina

Kannapolis, NC, 28081

Natalia Krupenko is an Assistant Professor with more than 20 years of experience researching the role of folate vitamin in health and disease. 

Honors and Awards

1st Place Poster Award
2012, Advances and Controversies in B-vitamins and Choline Conference, Leipzig, Germany

Key Publications

CerS6 is a Novel Transcriptional Target of p53 Activated by Non-Genotoxic Stress. Fekry B., Jeffries K.A., Esmaeilniakooshkghazi A., Ogretmen B., Krupenko S.A., Krupenko N.I. (2016). J Biol Chem, Jun 14.
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A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization. DebRoy S., Kramarenko I., Ghose S., Oleinik N.V., Krupenko S.A. and Krupenko N.I. (2013). PLOS One, 8(7).
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A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development. Christensen K.E., Deng L., Leung K.Y., Arning E., Bottiglieri T., Malysheva O.V., Caudill M.A., Krupenko N.I., Greene N.D., Jerome-Majewska L., MacKenzie R.E., Rozen R. (2013). Human Molecular Genetics, 22.
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Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6. Hoeferlin L.A., Fekry B., Krupenko S., Krupenko N.I. (2013). J Biol Chem, 288(18), 12880-12890.
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Molecular mechanisms underlying the potentially adverse effects of folate. Strickland K.C., Krupenko N.I., Krupenko S.A. (2013). Clin Chem Lab Med, 51(3), 607-616.
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Education

B.S., Biochemistry, Byelorussian State University, Minsk, USSR, 1980

Ph.D., Bioorganic Chemistry, Institute of Bioorganic Chemistry, Byelorussian Academy of Sciences, Minsk, USSR, 1987

The Rockefeller Foundation Fellow in Population Sciences, Center for Reproductive Biology Research, Vanderbilt University School of Medicine, 1994